Web28 lug 2024 · Treatment of Huh7 and Jeko-1 cells with SRX3177 abrogated binding of BRD4 to the MYC TSS, indicating that SRX3177 has pharmacodynamic activity against … Web10 apr 2024 · The JeKo-1 cell line was used for anti-tumor studies. Cells (10 × 10 6) in 100 μL of PBS were injected subcutaneously into the right flank of 6-week-old NSG female mice. Once tumors were palpable, the mice were randomized to different groups. Mice were treated i.p. with the ADC, and treatment periods were indicated by arrows.
JEKO1 DepMap Cell Line Summary
Web10 nov 2015 · To investigate molecular mechanisms at the basis of Chk1 inhibitor activity, a MCL cell line resistant to the Chk1 inhibitor PF-00477736 (JEKO-1 R) was obtained and characterized. The JEKO-1 R cell line was cross resistant to another Chk1 inhibitor (AZD-7762) and to the Wee1 inhibitor MK-1775. It displayed a shorter doubling time than … WebUnfortunately, malignant B cells are extremely difficult to transfect by most traditional methods. In this chapter, we describe the use of the Nucleofector™ Technology-based … is accounting 1 hard
Genes Free Full-Text Epigenetic Silencing of Tumor Suppressor ...
Web13 apr 2024 · We utilized the JeKo-1 cell line, a CD19-expressing mantle cell lymphoma model (Fig. S10A). To block mitochondrial apoptosis, we generated JeKo-1 variants … Web11 gen 2024 · Non-Hodgkin’s lymphoma (NHL) encompasses a heterogeneous group of diseases, including B-cell, T-cell and natural killer (NK)-cell lymphoma based on the origin and lineage of tumor cells [].B-cell lymphoma comprises more than 70% of all lymphomas, while T-cell lymphoma accounts for 10–15% of all lymphomas [].Diffuse large B-cell … WebDescription. GFP/Luc Reporter Cell Line - Jeko-1 is engineered to stably express GFP and luciferase encoding genes. This cell line is an ideal tool for fluorescent and bioluminescent tracing of Jeko-1 cells. JeKo-1 is a mantle cell lymphoma (MCL) cell line which is derived from peripheral blood mononuclear cells. old the blood of jesus lyrics