Cryptotanshinone supplement

Author: mqzm

August undefined, 2024

WebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone … WebJun 8, 2016 · -Methoxydalbergione (4-MD) -Curcumin -Thymoquinone (TQ) INHIBITION OF STAT3 ACTIVITY BY PHOSPHATASES -Acetoxychavicol acetate (ACA) -Guggulsterone (GS) -Hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) -Farnesol (FOH) -Capillarisin (CPS) MODULATION OF STAT3 ACTIVITY THROUGH ROS -Nimbolide (NL) -Shogaol (6SG) …

Bioavailability and pharmacokinetic comparison of tanshinones

WebOct 18, 2024 · Cryptotanshinone is a quinone diterpene extracted from the traditional Chinese medicine Salvia miltiorrhiza root that shows obvious anticancer activity. The aim … WebJun 11, 2024 · It is also used for menstrual disorders, chronic liver disease, and trouble sleeping caused by complaints such as rapid heartbeat and tight chest. Some people use … sharing ancestry tree

Danshen Uses, Benefits & Dosage - Drugs.com Herbal Database

WebTanshinone IIA (150) is the most abundant lipophilic compound in Danshen. Tanshinone I (144), cryptotanshinone (110 ), and 15,16-dihydrotanshinone I ( 51) are also the main constituents of the plant. Thus, the biological studies have prominently focused on these relatively abundant compounds. WebJul 1, 2024 · In this study, we studied the effect and epigenetic mechanisms of cryptotanshinone (CTS) and dihydrotanshinone (DHTS), the major active ingredients in Danshen, against human colorectal cancer HCT116 cells. WebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured … sharingan contacts sasuke

Cryptotanshinone - an overview ScienceDirect Topics

Cryptotanshinone Inhibits STAT3 Signaling to ... - Wiley Online Library

WebOct 5, 2024 · Cryptotanshinone is a major lipophilic compound extracted from the root of Danshen and has been reported to exert various pharmacological effects, however, its anti-cachectic remains unknown. Aim of the study: The present study aims to investigate the anti-cachectic efficacy of cryptotanshinone and elucidate the underlying mechanism. WebFeb 8, 2024 · In conclusion, while STAT3 regulates matrix metalloproteinase-9 and connective tissue growth factor expression in diabetic rats with cardiac fibrosis, cryptotanshinone inhibited fibrosis to improve cardiac function by suppressing the STAT3 pathway. Cryptotanshinone is suitable as an alternative remedy for therapy of cardiac … poppy best items tftWebBackground and purpose: Cryptotanshinone (CTS) is a major bioactive diterpenoid isolated from Danshen, an eminent medicinal herb that is used to treat cardiovascular disorders in … sharingan cursor

"WebJan 1, 2009 · Cryptotanshinone was identified as a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells and the growth of the cells through 96 hours of the treatment. " - Cryptotanshinone supplement

Cryptotanshinone supplement

Danshen Uses, Benefits & Dosage - Drugs.com Herbal Database

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WebNov 1, 2024 · To illustrate the synergistic antitumor effects of Cryptotanshinone and Paclitaxel on the expression of factors and proteins involving in cell apoptosis, cell cycle and metastasis induced by Cryptotanshinone and Paclitaxel, we detected the expression of STAT3, p-STAT3 (Try705), p-STAT3 (Ser727), Bcl-2, CDK2, MMP2, E-cadherin and β … WebSep 2, 2024 · Cryptotanshinone reduced the level of Aβ monomers and highly toxic oligomers in C. elegans while inhibiting the abnormal aggregation of polyglutamine protein. In addition, CTS upregulated the expression of hsp-16.2 and downregulated the expression of ace-2. These results suggested that CTS could alleviate oxidative stress and reduce the …

WebAug 21, 2024 · Cryptotanshinone (CTN), a monomer compound extracted from the dried roots and rhizomes of Salvia miltiorrhiza Bge, has a variety of pharmacological effects. However, little research has been done on the mechanism of CTN in attenuating neuroinflammation. WebTanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) …

WebFeb 1, 2024 · Cryptotanshinone (CTS) is a principal active constituent in Salvia miltiorrhiza Bunge (Danshen in Chinese), which is a widely used traditional Chinese medicine. CTS … WebNov 1, 2007 · It was found that cryptotanshinone inhibited the STAT3 tyrosine phosphorylation in DU145 prostate cancer cell in a dose-dependent manner. However, the …

WebJul 1, 2024 · Cryptotanshinone is a diterpene quinone derived from the roots of Salvia miltiorrhiza Bunge. An increasing number of studies have demonstrated that …

WebJun 26, 2013 · Though tanshinone IIA and cryptotanshinone possess a variety of biological effects such as anti-inflammatory, antioxidative, antimetabolic, and anticancer effects, the precise molecular targets or pathways responsible for anticancer activities of tanshinone IIA and cryptotanshinone in chronic myeloid leukemia (CML) still remain unclear. sharing ancestry dnaWebCryptotanshinone can induce the apoptosis of cancer cells by inhibiting PI3K/AKT, STAT3 signaling pathways, as well as transcription of MMP14, STAT3, and Nrf2 genes. The arrow … poppy beauty of livermereWebMar 2, 2024 · Cryptotanshinone (CPT), as a major component of Salvia miltiorrhiza Bunge (Danshen), displays many pharmacological activities including anti-inflammatory effects. However, the exact cellular and molecular mechanisms of the anti-inflammatory activities of CPT remain to be elucidated. The present study was aimed to clarify its mechanisms on … poppy bearWebNov 5, 2024 · Cryptotanshinone (CT) is an extract from the traditional Chinese medicine Salvia miltiorrhiza, which inhibits the growth of methicillin-resistant Staphylococcus … sharing and caring bentonvilleWebCryptotanshinone, a natural compound isolated from the roots of Salvia miltiorrhiza Bunge (Danshen), dramatically blocks STAT3 Tyr705 phosphorylation but not STAT3 Ser727 … poppy beifongWebModern pharmacological studies have shown that Cryptotanshinone has the effects of antibacterial, anti-inflammatory, antiobesity, and antidiabetic activity [ 12, 13] and has been prescribed for several diseases, including coronary heart disease (CHD), angina pectoris, and myocardial damage. sharingan copy and pasteWebCryptotanshinone: A review of its pharmacology activities and molecular mechanisms. As a natural quinone compound, the medicinal value of cryptotanshinone (CT) has received … poppy bird feeder amazon